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Therapeutic Exploitation of Apoptosis and Autophagy for Glioblastoma
Kogel D., Fulda S., Mittelbronn M.
Ganglioside GD3 as a Raft Component in Cell Death Regulation
Sorice M., Garofalo T., Misasi R., Manganelli V., Vona R., Malorni W.
Biology and Medicinal Chemistry Approaches Towards Various Apoptosis Inducers
K. Vyas V., Chintha C., R. Pandya M.
Doxycycline in Mitochondrial Mediated Pathway of Apoptosis: A Systematic Review
Sagar J., Sales K., Seifalian A., Winslet M.
Biological Potential of Halfsandwich Ruthenium(II) and Iridium (III) Complexes
Ludwig G., Mojić M., Bulatović M., Mijatović S., Maksimović-Ivanić D., Steinborn D., Kaluđerović G.
Neddylation Pathway as a Novel Anti-cancer Target: Mechanistic Investigation and Therapeutic Implication
Jiang Y., Jia L.
Anticancer Activity of Polyether Ionophore-Salinomycin
Antoszczak M., Huczyński A.
Anticancer Activity and Mechanism Investigation of Beauvericin Isolated from Secondary Metabolites of the Mangrove Endophytic Fungi
Tao Y., Lin Y., She Z., Lin M., Chen P., Zhang J.
Bleomycin Induced Sensitivity to TRAIL/Apo-2L-Mediated Apoptosis in Human Seminomatous Testicular Cancer Cells is Correlated with Upregulation of Death Receptors
Timur M., Cort A., Ozdemir E., Sarikcioglu S., Sanlioglu S., Sanlioglu A., Ozben T.
Modulation of Doxorubicin Mediated Growth Inhibition of Hepatocellular Carcinoma Cells by Platelet Lysates
Refolo M., D'Alessandro R., Lippolis C., Messa C., Carella N., Cavallini A., Carr B.
East-West Fusion–Necrosis and Apoptosis Acting in Concert by Demethylcantharidin-Integrated Platinum Complexes
Pang S., So W., Ho Y., Au-Yeung C.
β2-Microglobulin-mediated Signaling as a Target for Cancer Therapy
Nomura T., Huang W., Zhau H., Josson S., Mimata H., Chung L.
Focal Adhesion Kinase Regulates Expression of Thioredoxin-interacting Protein (TXNIP) in Cancer Cells
Ho B., Huang G., Golubovskaya V.
The Role of Autophagic Cell Death and Apoptosis in Irinotecan-treated p53 Null Colon Cancer Cells
John S., Mls J., Cervinka M., Rudolf E.
The Therapeutical Potential of a Novel Pterocarpanquinone LQB-118 to Target Inhibitor of Apoptosis Proteins in Acute Myeloid Leukemia Cells
R. de Souza Reis F., C. Casal de Faria F., P. Castro C., S. de Souza P., da Cunha Vasconcelos F., D. Bello R., J. da Silva A., R.R. Costa P., C. Maia R.
Dendrimer-Curcumin Conjugate: A Water Soluble and Effective Cytotoxic Agent Against Breast Cancer Cell Lines
Debnath S., Saloum D., Dolai S., Sun C., Averick S., Raja K., Fata J.
The Cytotoxic Effect of Emetine and CGP-74514A Studied with the Hollow Fiber Model and ArrayScan Assay in Neuroendocrine Tumors In Vitro
E. Larsson D., B. Hassan S., Oberg K., Granberg D.
Chemoprevention of Breast Cancer by Dietary Compounds
S. Vadodkar A., Suman S., Lakshmanaswamy R., Damodaran C.
Combination Therapy for the Treatment of Pancreatic Cancer
Greenhalf W., Thomas A.
Obesity Modulation - The Role in Carcinogenesis
Legakis I., Syrigos K.
Screening of Bioactive Fractions from Balanites aegyptiaca and Pterocarpus marsupium for Anticancer Effects in HepG2 and U87MG Cells
Vashishth D., Yadav M., Kumar A., Rohilla G., Vashist M., Kataria S.K.
Investigation of the Anticarcinogenic Effects of Hypericum perforatum Extract on Human Thyroid Cancer
Gokcek-Sarac C., Altunkaya G., Karakurt S.
Discovery of New Quinazoline Derivatives as VEGFR-2 Inhibitors: Design, Synthesis, and Anti-proliferative Studies
Dhawale S., Dabhade P., Mokale S.
The Effect of Iron Oxide Nanoparticles of Acalypha wilkesiana Ethyl Acetate Extract on Ehrlich Ascites Carcinoma Cells
Moustafa A., Abd El-Hamid El-Damrany M., Youssef M.
Genotoxicity and Anticancer Effects of the Aminothiophene Derivatives SB-44, SB- 83, and SB-200 in Cancer Cells
da Silva E., dos Santos F., de Oliveira J., dos Santos F., Junior F.J., do Carmo Alves de Lima M., da Rocha Pitta M., de Jesus de Melo Rego M., Pereira M.
Caracasine, An ent-kaurane Diterpene with Proapoptotic and Pro-differentiator Activity in Human Leukaemia Cell Lines
Martínez G., Mijares M., Chávez K., Chirinos P., Suárez A., Compagnone R., De Sanctis J.
Combination of Ethacrynic Acid and ATRA Triggers Differentiation and/or Apoptosis of Acute Myeloid Leukemia Cells through ROS
Cai X., Li L., Xi H., Lu H.
Lupiwighteone as an Antitumor Agent Reverses Multidrug Resistance in K562/ADR Cells by Regulating Cellular Prion Protein-Oct4 Axis
Hu K., Zhang J., Zhang Y., Wu X., Jin X., Mao S., Ding P., Wu S., Ren J.
A Novel Tryptanthrin Derivative D6 Induces Apoptosis and DNA Damage in Non-small-cell Lung Cancer Cells Through Regulating the EGFR Pathway
Long H., Zhang G., Zhou Y., Qin L., Zhu D., Chen J., Liu B., Tan H., Chen D., Li Z., Li C., Wang Z.
Anti-Cancer Activity of Synthesized 5-Benzyl juglone on Selected Human Cancer Cell Lines
Wang C., Hu Y., Sun Y., Xiang S., Qian J., Liu Z., Ji Y., Cai C., Sun G., Cui J.
Synthesis of Arylamino-1,3,5-triazines Functionalized with Alkylatin 2-chloroethylamine Fragments and Studies of their Cytotoxicity on the Breast Cancer MCF-7 Cell Line
Fraczyk J., Kolesinska B., Swiontek M., Lipinski W., Drozdowska D., Kaminski Z.
5-Lipoxygenase and Cyclooxygenase Inhibitory Dammarane Triterpenoid 1 from Borassus flabellifer Seed Coat Inhibits Tumor Necrosis Factor-α Secretion in LPSInduced THP-1 Human Monocytes and Induces Apoptosis in MIA PaCa-2 Pancreatic Cancer Cells
Sastry Yarla N., Azad R., Basha M., Rajack A., Kaladhar D.S., Kumar Allam B., Rao. Pragada R., Nand Singh K., Kumari K S., Pallu R., Parimi U., Bishayee A., Rao. Duddukuri G.
Recent Developments Towards Podophyllotoxin Congeners as Potential Apoptosis Inducers
Kamal A., Ali Hussaini S., Malik M.
HUHS1015 Induces Necroptosis and Caspase-Independent Apoptosis of MKN28 Human Gastric Cancer Cells in Association with AMID Accumulation in the Nucleus
Kaku Y., Tsuchiya A., Kanno T., Nishizaki T.
Deoxypodophyllotoxin Isolated from Juniperus communis Induces Apoptosis in Breast Cancer Cells
Benzina S., Harquail J., Jean S., Beauregard A., Colquhoun C., Carroll M., Bos A., Gray C., Robichaud G.
Cucurbitacin B Induces DNA Damage, G2/M Phase Arrest, and Apoptosis Mediated by Reactive Oxygen Species (ROS) in Leukemia K562 Cells
Guo J., Zhao W., Hao W., Ren G., Lu J., Chen X.
α-Methylene-γ-lactones as a Novel Class of Anti-leukemic Agents
Gach K., Janecka A.
Green Tea Catechins: Proposed Mechanisms of Action in Breast Cancer Focusing on the Interplay Between Survival and Apoptosis
Yiannakopoulou E.
Glaucocalyxin A and B-induced Cell Death is Related to GSH Perturbation in Human Leukemia HL-60 Cells
Yang W., Zhang Z., Sima Y., Zhang J., Wang J.
NF-κB Down–regulation and PARP Cleavage by novel 3-α-butyryloxy-β-boswellic Acid Results in Cancer Cell Specific Apoptosis and in vivo Tumor Regression
Qurishi Y., Hamid A., Sharma P.R., Wani Z.A., Mondhe D.M., Singh S.K., Zargar M.A., Andotra S.S., Shah B.A., Taneja S.C., Saxena A.K.
The Role of Mesothelin in Tumor Progression and Targeted Therapy
Tang Z., Qian M., Ho M.
New Insight into P-Glycoprotein as a Drug Target
Breier A., Gibalova L., Seres M., Barancik M., Sulova Z.
Regulation of MMPs During Melanoma Progression: From Genetic to Epigenetic
Antonicelli F., Vallerand D., Trussardi-Regnier A., Grange F., Hornebeck W., Bernard P.
Ceramide and Apoptosis: Exploring the Enigmatic Connections between Sphingolipid Metabolism and Programmed Cell Death
Mullen T.D., Obeid L.M.
Cancer Prevention with Promising Natural Products: Mechanisms of Action and Molecular Targets
Pratheeshkumar P., Sreekala C., Zhang Z., Budhraja A., Ding S., Son Y., Wang X., Hitron A., Hyun-Jung K., Wang L., Lee J., Shi X.
Molecular Mechanisms of Anti-cancer Action of Garlic Compounds in Neuroblastoma
Karmakar S., Roy Choudhury S., L. Banik N., K. Ray S.
Exploiting Cyclooxygenase-(in)Dependent Properties of COX-2 Inhibitors for Malignant Glioma Therapy
H. Schonthal A.
In vitro and In vivo Growth Inhibition and Apoptosis of Cancer Cells by Ethyl 4-[(4-methylbenzyl)oxy] Benzoate Complex
Auwal A., Al Banna M.H., Pronoy T., Hossain M.M., Rashel K., Kabir S.R., Ansary M.R., Islam F.
Combined Application of Salinomycin and ATRA Induces Apoptosis and Differentiation of Acute Myeloid Leukemia Cells by Inhibiting WNT/β-Catenin Pathway
Xi H., Lu H., Weng X., Sheng Y., Wu J., Li L., Cai X.
Pulsatilla saponin A Inhibits Proliferation and Induces Apoptosis in Diffuse Large Bcell Lymphoma Cells through the JAK2/STAT3 Signaling Pathway
Liu N., Zhan X., Bai J., Yu H., Chen X., Kong X., Ni H.
Synthesis and Characterization of Novel 4-aryl-4H-chromene Derivatives using Borax and Evaluation of their Anticancer Effects
Adibi H., Hosseinzadeh L., Amirafshari M., Jalilian F.
3-Bromopyruvate Inhibits the Growth and Glucose Metabolism of TNBC Xenografts in Nude Mice by Targeting c-Myc
Pan J., Li J., Yang C., Xiao W., Li Q., Luo X., Zhang X.
Molecular Mechanisms of Chloroquine and Hydroxychloroquine Used in Cancer Therapy
De Sanctis J., Charris J., Blanco Z., Ramírez H., Martínez G., Mijares M.
Synthesis of a Novel Gold(I) Complex and Evaluation of Its Anticancer Properties in Breast Cancer Cells
Khan H., Isab A., Alhomida A., Gatasheh M., Alhoshani A., Aldhafeeri B., Prasad N.
FN-1501 Inhibits Diffuse Large B-Cell Lymphoma Tumor Growth by Inducing Cell Cycle Arrest and Apoptosis
Feng S., Si R., Zhong B., Shen B., Du Y., Feng J., Zou D., Hu B.
Resveratrol Inhibits Nasopharyngeal Carcinoma (NPC) by Targeting the MAPK Signaling Pathway
Yi Y., Zhou B., Man T., Xu Z., Tang H., Li J., Sun Z.
Anti-tumoral Immunity and Chemo-preventive Effectiveness of Herbal Extracts of Curcumin, Ginger, Clove and Amygdaline in Ehrlich Ascites Carcinoma-Challenging Mice
Gomaa S., Nassef M., El-Naggar R., Massoud A., El-Kholy M.
Indole Derivatives as Anticancer Agents for Breast Cancer Therapy: A Review
Sidhu J., Singla R., Mayank , Jaitak V.
Heterocyclic Drug-polymer Conjugates for Cancer Targeted Drug Delivery
Kaur H., Desai S., Kumar V., Rathi P., Singh J.
4,6-diaryl Pyrimidones as Constrained Chalcone Analogues: Design, Synthesis and Evaluation as Antiproliferative Agents
Kumar D., Nepali K., Bedi P., Kumar S., Malik F., Jain S.
Epoxomicin Sensitizes Resistant Osteosarcoma Cells to TRAIL Induced Apoptosis
Hanikoglu F., Cort A., Ozben H., Hanikoglu A., Ozben T.
Cystine Dimethyl Ester Induces Apoptosis Through Regulation of PKC-δ and PKC-ε in Prostate Cancer Cells
Gurbuz N., Park M., Dent P., Abdel Mageed A., Sikka S., Baykal A.
A Review on Antiproliferative and Apoptotic Activities of Natural Honey
Jaganathan S., Balaji A., Vellayappan M., Asokan M., Subramanian A., John A., Supriyanto E., Razak S., Marvibaigi M.
Baicalin Induces Apoptosis of Gallbladder Carcinoma Cells in vitro via a Mitochondrial-Mediated Pathway and Suppresses Tumor Growth in vivo
Shu Y., Bao R., Wu X., Weng H., Ding Q., Cao Y., Li M., Mu J., Wu W., Ding Q., Liu T., Jiang L., Hu Y., Tan Z., Wang P., Liu Y.
Combining Anti-tumor Alkyl-Phospholipid Analogs and Radiotherapy: Rationale and Clinical Outlook
Verheij M., Moolenaar W., Blitterswijk W.
Synthesis, Preferentially Hypoxic Apoptosis and Anti-Angiogenic Activity of 3- Amino-1,2,4-Benzotriazine-1,4-Dioxide Bearing Alkyl Linkers with a 3-Amino-1,2,4- Benzotriazine-1-Oxide Moiety
Lee C., Huang C., Huang W., Lee A.
Muscarinic Activation Enhances the Anti-proliferative Effect of Paclitaxel in Murine Breast Tumor Cells
Español A., Jacob G., Dmytrenko G., Sales M.
Inhibition of PCAF by Anacardic Acid Derivative Leads to Apoptosis and Breaks Resistance to DNA Damage in BCR-ABL-expressing Cells
Kobialka M.K., Ruszkowska W.D., Ghizzoni M., Dekker F.J., Piwocka K.
Effects of Limonoid Cedrelone on MDA-MB-231 Breast Tumor Cells in vitro
Fuzer A., Filho J., Becceneri A., Santos D., Silva M., Vieira P., Fernandes J., Selistre-de-Araujo H., Cazal C., Cominetti M.
The Anti-cancer Actions of Vitamin D
Chiang K., C. Chen T.
A New 4-phenyl-1,8-naphthyridine Derivative Affects Carcinoma Cell Proliferation by Impairing Cell Cycle Progression and Inducing Apoptosis
Capozzi A., Mantuano E., Matarrese P., Saccomanni G., Manera C., Mattei V., Gambardella L., Malorni W., Sorice M., Misasi R.
Cholesterol, Cardiolipin, and Mitochondria Permeabilisation
Lucken-Ardjomande Hasler S.
Natural Products: Promising Resources for Cancer Drug Discovery
Mondal S., Bandyopadhyay S., K. Ghosh M., Mukhopadhyay S., Roy S., Mandal C.
Anticancer Effects of Garlic and Garlic-derived Compounds for Breast Cancer Control
Tsubura A., Lai Y., Kuwata M., Uehara N., Yoshizawa K.
Quercetin Suppresses Glioma Stem Cells via Activating p16-INK4 Gene Expression through Epigenetic Regulation
Li J., Li J., Guo E.
Mechanisms of Cancer-killing by Quercetin; A Review on Cell Death Mechanisms
Wang H., Dong Z., Liu J., Zhu Z., Najafi M.
Inhibition of Ribonucleotide Reductase Induces Endoplasmic Reticulum Stress and Apoptosis, Leading to the Death of Docetaxel-resistant Prostate Cancer Cells
Serttas R., Erdogan S.
Berbamine Inhibits the Biological Activities of Prostate Cancer Cells by Modulating the ROS/NF-κB Axis
Zhao W., Jiang Y., Jia X., Wang X., Guo Y.
Novel 5-bromoindole-2-carboxylic Acid Derivatives as EGFR Inhibitors: Synthesis, Docking Study, and Structure Activity Relationship
Hassan O., Kubba A., Tahtamouni L.
Azidothymidine is Effective Against Human Multiple Myeloma: A New Use for an Old Drug?
Pereira J., Levy D., L.M. Ruiz J., A. Brocardo G., A. Ferreira K., O. Costa R., G. Queiroz R., A. Maria D., E. Hallack Neto A., A.F. Chamone D., P. Bydlowski S.
Ivermectin Inhibits Bladder Cancer Cell Growth and Induces Oxidative Stress and DNA Damage
Fan N., Zhang L., Wang Z., Ding H., Yue Z.
Preparation of Lycium barbarum Active Glycopeptide and Investigation of Its Apoptotic Effects on Melanoma
Qi J., Qi X., Chen H., Rui W.
Optimizing Coreopsis tinctoria Flower Extraction and Inhibiting CML Activity: Box-Behnken Design
Chen X., Zhou X., Gao Y.
Investigating the Effects of Dorema hyrcanum Root Extracts on Selective Induction of Programmed Cell Death in Glioblastoma, Ovarian Cancer and Breast Cancer Cell Lines
Shandi M., Sahranavard S., Bagheri F., Shahsavari Z., Salami S.
In Vitro Anticancer Effects of Two New Potent Hydrazide Compounds on Leukemic Cells
Tavakolfar S., Mousavi E., Almasirad A., Amanzadeh A., Atyabi S., Yaghamii P., Samiee-Sadr S., Salimi M.
Macromolecular Drug Targets in Cancer Treatment and Thiosemicarbazides as Anticancer Agents
Küçükgüzel Ş., Coşkun G.
A Novel Cobalt(II) Coordination Complex Constructed from H2Pyri and 4,4′-Bipy: Synthesis, Characterization and Bioactivity
Gao E., Zhao F., Zhu M., Wang M.
Molecular Mechanism Behind the Synergistic Activity of Diphenylmethyl Selenocyanate and Cisplatin Against Murine Tumor Model
Chakraborty P., Roy S., Bhattacharya S.
Chrysin Induces Apoptosis in Peripheral Blood Lymphocytes Isolated from Human Chronic Lymphocytic Leukemia
Zaric M., Mitrovic M., Nikolic I., Baskic D., Popovic S., Djurdjevic P., Milosavljevic Z., Zelen I.
Chalcones Incorporated Pyrazole Ring Inhibit Proliferation, Cell Cycle Progression, Angiogenesis and Induce Apoptosis of MCF7 Cell Line
Mohamed M., Mohamed M., Fathi M., Shouman S., Abdelhamid I.
ent-Kaurane Diterpenoids from Croton tonkinensis Induce Apoptosis in Colorectal Cancer Cells through the Phosphorylation of JNK Mediated by Reactive Oxygen Species and Dual-Specificity JNK Kinase MKK4
Thuong P., Khoi N., Ohta S., Shiota S., Kanta H., Takeuchi K., Ito F.
Glycosidated Phospholipids – a Promising Group of Anti-Tumour Lipids
Semini G., Hildmann A., Haefen C., Danker K.
Bergamot Juice Extract Inhibits Proliferation by Inducing Apoptosis in Human Colon Cancer Cells
Visalli G., Ferlazzo N., Cirmi S., Campiglia P., Gangemi S., Pietro A., Calapai G., Navarra M.
Omega-3 Polyunsaturated Fatty Acids and Cancer
Jing K., Wu T., Lim K.
N6-Isopentenyladenosine and its Analogue N6-Benzyladenosine Induce Cell Cycle Arrest and Apoptosis in Bladder Carcinoma T24 Cells
Castiglioni S., Casati S., Ottria R., Ciuffreda P., A.M. Maier J.
Discovery and Hit to Lead Optimization of Novel Combretastatin A-4 Analogues: Dependence of C-Linker Length and Hybridization
Provot O., Hamze A., Peyrat J., Brion J., Alami M.
The Role of Peroxisome Proliferator-Activated Receptor-γ in Breast Cancer
Kotta-Loizou I., Giaginis C., Theocharis S.
Effects of Bioactive Compounds from Carrots (Daucus carota L.), Polyacetylenes, Beta-Carotene and Lutein on Human Lymphoid Leukaemia Cells
G. Zaini R., Brandt K., R. Clench M., L. Le Maitre C.
Alteration of Ceramide 1-O-Functionalization as a Promising Approach for Cancer Therapy
Ballereau S., Levade T., Genisson Y., Andrieu-Abadie N.
The Gut-To-Breast Connection - Interdependence of Sterols and Sphingolipids in Multidrug Resistance and Breast Cancer Therapy
Spassieva S., Bieberich E.
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