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Recent Development in Targeting PI3K-Akt-mTOR Signaling for Anticancer Therapeutic Strategies
Qazi A., Hussain A., Hamid A., Qurishi Y., Majeed R., Ahmad M., Najar R., Bhat J., Singh S., Zargar M., Ali S., Saxena A.
Selected Approaches for Rational Drug Design and High Throughput Screening to Identify Anti-Cancer Molecules
Sarkar S., B. Fisher P., Sarkar D., Pellecchia M., C. Reed J., W. Diaz P., L. Stebbins J., Wu B., Wei J., G. Pomper M., Wang X., Bhoopathi P., E. Menezes M., Erdogan E., Hedvat M., K. Sokhi U., P. Kegelman T., A. Oyesanya R., A. Quinn B., Dash R., Zhu S., Hu B., Thomas S., Dasgupta S., Kim K., K. Das S., Emdad L.
MicroRNAs in Cancer: Small Molecules, Big Chances
Abba M., Mudduluru G., Allgayer H.
Anticoagulant and Fibrinolytic Drugs – Possible Agents in Treatment of Lung Cancer?
Bobek V.
Developing Phytoestrogens for Breast Cancer Prevention
M. Liu M., Huang Y., Wang J.
Development of NGR-Based Anti-Cancer Agents for Targeted Therapeutics and Imaging
E. Wang R., Niu Y., Wu H., Hu Y., Cai J.
Regulation of Sphingosine Kinase in Hematological Malignancies and Other Cancers
M. Pitson S., A. Powell J., S. Bonder C.
Role of Stem Cells in Normal Liver and Cancer
Keung Lau C., Fan Yang Z., Tat Fan S.
Insulin-Like Growth Factor Signaling as a Therapeutic Target in Pancreatic Cancer
Rieder S., W. Michalski C., Friess H., Kleeff >.
Redox-Active Quinones and Ascorbate: An Innovative Cancer Therapy That Exploits the Vulnerability of Cancer Cells to Oxidative Stress
Verrax J., Beck R., Dejeans N., Glorieux C., Sid B., C. Pedrosa R., Benites J., Vasquez D., A. Valderrama J., Buc Calderon P.
SHP-1 in Cell-Cycle Regulation
Lopez-Ruiz P., Rodriguez-Ubreva J., Ernesto Cariaga A., Alicia Cortes M., Colas B.
Updates of mTOR Inhibitors
Zhou H., Luo Y., Huang S.
Proteomic and Metallomic Strategies for Understanding the Mode of Action of Anticancer Metallodrugs
Gabbiani C., Magherini F., Modesti A., Messori L.
In vivo, In vitro, and In silico Studies of Umbelliferone and Irinotecan on MDA-MB-231 Breast Cancer Cell Line and Drosophila melanogaster Larvae
Tamturk E., Yalcın S., Ercan F., Tuncbilek A.
Curcumin and its Analogues in Oral Squamous Cell Carcinoma: State-of-the-art and Therapeutic Potential
Schiavoni V., Emanuelli M., Sartini D., Salvolini E., Pozzi V., Campagna R.
Pioneering the Battle Against Breast Cancer: The Promise of New Bcl-2 Family
Boroujeni A., Ates-Alagoz Z.
Molecular Dynamics (MD) Simulation of GPR87-LPA Binding: Therapeutic Implications for Targeted Cancer Treatment
Rani M., Sharma A., Nischal A., Khattri S., Sahoo G., Singh R.
Precision Therapy for Prostate Cancer: Advancements in Polymeric Nanocarrier Systems
Kumar L., Rana R., Shaikh N., Kumar S., Aggarwal V., Komal K., Jyothiraditya V.
Anti-metastasis Effects and Mechanism of Action of Curcumin Analog (2E,6E)-2,6-bis(2,3-dimethoxybenzylidene) Cyclohexanone (DMCH) on the SW620 Colorectal Cancer Cell Line
Rahim N., Hussin Y., Aziz M., Masarudin M., Gani S., Akhtar M., Abd. Rahman N.M., Alitheen N.
Ginsenoside Rb1 Suppresses AOM/DSS-induced Colon Carcinogenesis
Wang L., Zhang Q., Xu Y., Zhang R., Zhao Q., Zhang Y., Huang X., Jiang B., Ni M.
In silico Screening and Validation of Achyranthes aspera as a Potential Inhibitor of BRAF and NRAS in Controlling Thyroid Cancer
Alamri A., Alkhilaiwi F., Khan N., Tasleem M.
Design and Evaluation of SLNs Encapsulated Curcumin-based Topical Formulation for the Management of Cervical Cancer
Singhai M., Pandey V., Ashique S., Gupta G., Arora D., Haider T., Mishra N.
Antitumor Mechanisms of Molecules Secreted by Trypanosoma cruzi in Colon and Breast Cancer: A Review
Sadr S., Ghiassi S., Lotfalizadeh N., Simab P., Hajjafari A., Borji H.
Recent Advancement in the Inhibition of Triple-negative Breast Cancer by N-heterocycles
Choudhury B., Chanda K.
Gambogic Acid Lysinate-induced Cervical Cancer SiHa Cells Apoptosis in vitro and in vivo
Sun J., Liu Y., Guo J., Zhang X., Lin Y., Niu J.
CYP24A1 as a Potential Target for Cancer Therapy
Sakaki T., Yasuda K., Kittaka A., Yamamoto K., Chen T.
Hyperoside Inhibits RNF8-mediated Nuclear Translocation of β-catenin to Repress PD-L1 Expression and Prostate Cancer
Chen J., Zhao Y., Wang X., Zang L., Yin D., Tan S.
Overview of the New Bioactive Heterocycles as Targeting Topoisomerase Inhibitors Useful Against Colon Cancer
Santos M., de Azevedo Teotônio Cavalcanti M., de Medeiros e Silva Y.M., dos Santos Nascimento I., de Moura R.
Antitumoral Potential of Artepillin C, a Compound Derived from Brazilian Propolis, against Breast Cancer Cell Lines
de Freitas Meirelles L., de Assis Carvalho A., Ferreira Damke G., Souza R., Damke E., de Souza Bonfim-Mendonça P., de Oliveira Dembogurski D., da Silva D., Consolaro M., da Silva V.
Silibinin Induces Both Apoptosis and Necroptosis with Potential Anti-tumor Efficacy in Lung Cancer
Zhang G., Wang L., Zhao L., Yang F., Lu C., Yan J., Zhang S., Wang H., Li Y.
Arsenic Trioxide Suppresses Angiogenesis in Non-small Cell Lung Cancer via the Nrf2-IL-33 Signaling Pathway
Wang M., Yin J., Han Q., Li B., Zhao X., Xue L.
Ginsenoside Rb1 Inhibits the Proliferation of Lung Cancer Cells by Inducing the Mitochondrial-mediated Apoptosis Pathway
Feng L., Liu X., Sun K., Sun Y., Wu W., Chen C., Jin X., Wan X.
In Vitro Anticancer Effects of Two New Potent Hydrazide Compounds on Leukemic Cells
Tavakolfar S., Mousavi E., Almasirad A., Amanzadeh A., Atyabi S., Yaghamii P., Samiee-Sadr S., Salimi M.
Design and Synthesis of Some Novel Estrogen Receptor Modulators as Anti-Breast Cancer Agents: In Vitro & In Vivo Screening, Docking Analysis
Dube P., Mokale S.
Synthesis of Diflunisal Thiazolidinones as Anticancer Agents
Şenkardeş S., Özakpınar Ö., Özsavcı D., Şener A., Çevik Ö., Küçükgüzel Ş.
Therapeutic Use of MicroRNAs in Cancer
Tessitore A., Cicciarelli G., Mastroiaco V., Del Vecchio F., Capece D., Verzella D., Fischietti M., Vecchiotti D., Zazzeroni F., Alesse E.
A Role for the Inflammatory Mediators Cox-2 and Metalloproteinases in Cancer Stemness
Chimal-Ramírez G., Espinoza-Sanchez N., Fuentes-Panana E.
Berberine Exhibits Antitumor Effects in Human Ovarian Cancer Cells
Jin P., Zhang C., Li N.
Immune Checkpoint Inhibitors for Non-small-cell Lung Cancer: Does that Represent a ‘New Frontier’?
Pilotto S., Kinspergher S., Peretti U., Calio A., Carbognin L., Ferrara R., Brunelli M., Chilosi M., Tortora G., Bria E.
Mitogen-activated Protein Kinase Kinase 6-fusion Protein (MAP2K6-FP) Potentiates the Anti-tumor effects of Paclitaxel in Ovarian Cancer
Yuan J., Kang J., Liao H., Wang X., Nie M., Shuai R., Deng C.
A Review on Antiproliferative and Apoptotic Activities of Natural Honey
Jaganathan S., Balaji A., Vellayappan M., Asokan M., Subramanian A., John A., Supriyanto E., Razak S., Marvibaigi M.
Organometallic Compounds in Cancer Therapy: Past Lessons and Future Directions
Martins P., Marques M., Coito L., Pombeiro A., Baptista P., Fernandes A.
EGFRIndb: Epidermal Growth Factor Receptor Inhibitor Database
Yadav I., Singh H., Khan M., Chaudhury A., Raghava G., Agarwal S.
Curcumin: A Promising Agent Targeting Cancer Stem Cells
Zang S., Liu T., Shi J., Qiao L.
Targeted Anti-HER2 Cancer Therapy in Elderly Women Diagnosed with Breast Cancer
Molina-Garrido M., Guillen-Ponce C., Mora-Rufete A.
Therapeutic Vaccines Explored in Patients with Non-Small Cell Lung Cancer
Ma K., Tang Y.
Pro-Oxidative Action of Polyphenols as Action Mechanism for their Pro-Apoptotic Activity
Lecci R., Logrieco A., Leone A.
Intracellular Expression of Inflammatory Proteins S100A8 and S100A9 Leads to Epithelial-mesenchymal Transition and Attenuated Aggressivity of Breast Cancer Cells
Ouellette R., Tessier P., Guerrette R., Robichaud G., Cormier K., Harquail J.
Oxaliplapin and Capecitabine (XELOX) Based Chemotherapy in the Treatment of Metastatic Colorectal Cancer: The Right Choice in Elderly Patients
Berretta M., Aprile G., Nasti G., Urbani M., Bearz A., Lutrino S., Foltran L., Ferrari L., Talamini R., Fiorica F., Lleshi A., Canzonieri V., Lestuzzi C., Borsatti E., Fisichella R., Tirelli U.
Tocotrienols Target PI3K/Akt Signaling in Anti-Breast Cancer Therapy
Sylvester P., Ayoub N.
Cucurmosin Kills Human Pancreatic Cancer SW-1990 Cells in vitro and in vivo
Xie J., Wang C., Yang A., Zhang B., Yin Q., Huang H., Chen M.
Integrated Therapeutic Approaches in Head and Neck Cancer: The Importance of Multidisciplinary Team Management
Perri F., Muto P., Aversa C., Daponte A., Vittoria G., Pepe S., Caponigro F.
β -Glucans and their Applications in Cancer Therapy: Focus on human studies
Aleem E.
Mitoxantrone Targets the ATP-binding Site of FAK, Binds the FAK Kinase Domain and Decreases FAK, Pyk-2, c-Src, and IGF-1R In Vitro Kinase Activities
M. Golubovskaya V., Ho B., Zheng M., Magis A., Ostrov D., G. Cance W.
DNA Methylation as a Target of Epigenetic Therapeutics in Cancer
K. Li K., Li F., S. Li Q., Yang K., Jin B.
Dendrimer-Curcumin Conjugate: A Water Soluble and Effective Cytotoxic Agent Against Breast Cancer Cell Lines
Debnath S., Saloum D., Dolai S., Sun C., Averick S., Raja K., Fata J.
Anti-cancer Effects of Curcumin on Head and Neck Cancers
Gao W., Yu-Wai Chan J., Ignance Wei W., Wong T.
Immunomodulation and Anti-inflammatory Roles of Polyphenols as Anticancer Agents
Ghiringhelli F., Rebe C., Hichami A., Delmas D.
Inhibiting Matrix Metalloproteinases, an Old Story with New Potentials for Cancer Treatment
Stellas D., Patsavoudi E.
Neutrophil Elastase as a Target in Lung Cancer
Moroy G., J.P. Alix A., Sapi J., Hornebeck W., Bourguet E.
Procathepsin D as a Tumor Marker, Anti-Cancer Drug or Screening Agent
Vetvicka V., Fusek M.
Targeting Cancer Using Fragment Based Drug Discovery
P. Turnbull A., M. Boyd S.
Sphingolipid Signaling and Hematopoietic Malignancies: To the Rheostat and Beyond
C. Loh K., Baldwin D., D. Saba J.
Molecular Mechanisms of Liver Cancer
Pan H., Fu X., Huang W.
Combination Therapy for the Treatment of Pancreatic Cancer
Greenhalf W., Thomas A.
PTPN13/PTPL1: An Important Regulator of Tumor Aggressiveness
Freiss G., Chalbos D.
Epidermal Growth Factor Receptor as a Target for Anti-Cancer Agent Design
Cao J., Fang H., Wang B., Ma C., Xu W.
Mechanisms of Cytotoxicity of Anticancer Titanocenes
Olszewski U., Hamilton G.
Tumor Initiation in Human Malignant Melanoma and Potential Cancer Therapies
Ma J., Frank M.
Application of Biological Study for Met Expression to Cancer Therapy
Osada S., Yoshida K.
An Updated Review on Dysregulated lncRNAs and their Contribution to the Various Molecular Types of Lung Carcinoma
Dastmalchi N., Alipour M., Safaralizadeh R., Hajiasgharzadeh K.
Advancements in Pyrazine Derivatives as Anticancer Agents: A Comprehensive Review (2010-2024)
Alshahrani M.
A Path to the Formation Mechanism of Propolis Nanoparticles, their Cytotoxicity on 3T3 Fibroblasts, Metastatic Murine B16F10 Cells, and their In vivo Irritability in Animals
Gonzalez-Masis J., Gonzalez-Paz R., Urena Y., Guerrero S., Gonzalez-Camacho S., Mora-Ugalde N., Baizan-Rojas M., Loaiza R., Vega-Baudrit J., Cubero-Sesin J.
Computational Modelling Strategies for Exploring Triazolopyridazine PIM1 Kinase Inhibitors as Anticancer Agents
Walhekar V., Bagul C., Kumar D., Achaiah G., Muthal A., Kulkarni R., Basavarju M.
Royal Jelly's Strong Selective Cytotoxicity Against Lung Malignant Cells and Macromolecular Alterations in Cells Observed by FTIR Spectroscopy
Aysin f.
Synthetic Methodologies and SAR of Quinazoline Derivatives as PI3K Inhibitors
Raj A., Kumar A., Singh A., Singh H., Thareja S., Kumar P.
A Systematic Review and Meta-analysis on the Role of Statins in the Prevention of Mortality Following Pancreatic Cancer
Anbari K., Amiri M., Heidari-Soureshjani S., Sherwin C., Kasiri K.
MDM2-mediated Inhibitory Effect of Arsenic Trioxide on Small Cell Lung Cancer Cell Line by Degrading Mutant p53
Wang Y., Yin J., Shi X., Zhao X., Li B., Yang M.
Assessment of Cytotoxic/Antitumour Potential and in silico Study of Salazinic Acid Isolated from Parmotrema concurrens
da Conceição de Lira M., da Silva M., Rocha T., de Moura D., Santos Costa E., dos Santos Maia M., Scotti L., Scotti M., de Lourdes Lacerda Buril M., Pereira E., de Aguiar Júnior F.C., de Britto Lira Nogueira M., da Silva Santos N., da Silva Falcão E., de Melo S.
Phytochemicals in the Synthetic Era: A Potential Oncosuppressor against Cancer Stem Cells
Maru D., Kumar A.
Cytochromes P450 and Skin Cancer: Role of Local Endocrine Pathways
Slominski A., Zmijewski M., Semak I., Zbytek B., Pisarchik A., Li W., Zjawiony J., Tuckey R.
Cordyceps militaris: A Comprehensive Study on Laboratory Cultivation and Anticancer Potential in Dalton's Ascites Lymphoma Tumor Model
Dutta D., Singh N., Aggarwal R., Verma A.
Design, Synthesis, and In vitro Anti-cervical Cancer Activity of a Novel MDM2-p53 Inhibitor Based on a Chalcone Scaffold
Alimujiang Y., Maimaiti A., Ablise M., Yang Z., Liu Z., Wang Y., Mutalipu Z., Yan T.
Novel Anti-tumor Strategy for Breast Cancer: Synergistic Role of Oleuropein with Paclitaxel Therapeutic in MCF-7 Cells
Yılmaz G., Özdemir F.
Chalcones as Potential Cyclooxygenase-2 Inhibitors: A Review
Mahboubi-Rabbani M., Zarei R., Baradaran M., Bayanati M., Zarghi A.
Application of Nanoparticles in the Diagnosis and Treatment of Colorectal Cancer
Song Q., Zheng Y., Zhong G., Wang S., He C., Li M.
Preparation of a Novel Multifunctional Cationic Liposome Drug-carrying System and its Functional Study on Lung Cancer
Kong Y., Xu L., Cao J.
Wortmannin Inhibits Cell Growth and Induces Apoptosis in Colorectal Cancer Cells by Suppressing the PI3K/AKT Pathway
Bani N., Rahmani F., Shakour N., Amerizadeh F., Khalili-Tanha G., Khazaei M., Hassanian S.M., Kerachian M.A., Abbaszadegan M.R., Mojarad M., Hadizadeh F., Ferns G., Avan A.
Anticancer Activity of Sargassum fluitans Extracts in Different Cancer Cells
González-Garrido J., Gómez-García J., Hernández-Abreu O., Olivares-Corichi I., Pereyra-Vergara F., García-Sánchez J.
In Vivo Inhibition of Proteasome Activity and Tumour Growth by Murraya koenigii Leaf Extract in Breast Cancer Xenografts and by Its Active Flavonoids in Breast Cancer Cells
Noolu B., Gogulothu R., Bhat M., Qadri S., Reddy V., Reddy G., Ismail A.
Molecular Mechanisms of Anti-cancer Activities of β-elemene: Targeting Hallmarks of Cancer
Jiang S., Ling C., Li W., Jiang H., Zhi Q., Jiang M.
Diazenyl Derivatives and their Complexes as Anticancer Agents
Kaur H., Yadav S., Narasimhan B.
Design, Synthesis, and Evaluation of Genistein Analogues as Anti-Cancer Agents
Xiong P., Wang R., Zhang X., DeLa Torre E., Leon F., Zhang Q., Zheng S., Wang G., Chen Q.
In Vivo Anticancer Activity, Toxicology and Histopathological Studies of the Thiolate Gold(I) Complex [Au(Spyrimidine)(PTA-CH2Ph)]Br
Garcia-Moreno E., Gascon S., Garcia de Jalon J., Romanos E., Rodriguez-Yoldi M., Cerrada E., Laguna M.
Differential Interactions of Cytochrome P450 3A5 and 3A4 with Chemotherapeutic Agent-Vincristine: A Comparative Molecular Dynamics Study
Saba N., Bhuyan R., Nandy S., Seal A.
HUHS1015 Induces Necroptosis and Caspase-Independent Apoptosis of MKN28 Human Gastric Cancer Cells in Association with AMID Accumulation in the Nucleus
Kaku Y., Tsuchiya A., Kanno T., Nishizaki T.
Revision of the Synthesis and Pharmacological Activity of a Reported Translation Inhibitor
Basmadjian C., Malka-Mahieu H., Desaubry L.
Tea (Camellia sinensis (L.)): A Putative Anticancer Agent in Bladder Carcinoma?
Conde V., Alves M., Oliveira P., Silva B.
Differential Role of Apoptosis and Autophagy Associated with Anticancer Effect of Lupulone (Hop β-Acid) Derivatives on Prostate Cancer Cells
Mouratidis P., Colston K., Charolidi N., Pirianov G.
Role of Caspases, Bax and Bcl-2 in Chrysin-Induced Apoptosis in the A549 Human Lung Adenocarcinoma Epithelial Cells
Samarghandian S., Nezhad M., Mohammadi G.
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