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Type II Kinase Inhibitors: An Opportunity in Cancer for Rational Design
Blanc J., Geney R., Menet C.
Recent Developments on Thiourea Based Anticancer Chemotherapeutics
Kumar V., Chimni S.
Recent Developments of Small Molecule EGFR Inhibitors Based on the Quinazoline Core Scaffolds
Liu Y., Zhang C., Liu Z.
Therapeutic Exploitation of Apoptosis and Autophagy for Glioblastoma
Kogel D., Fulda S., Mittelbronn M.
EGFRIndb: Epidermal Growth Factor Receptor Inhibitor Database
Yadav I., Singh H., Khan M., Chaudhury A., Raghava G., Agarwal S.
Downregulation of Hypoxia-related Responses by Novel Antitumor Histone Deacetylase Inhibitors in MDAMB231 Breast Cancer Cells
Naldini A., Filippi I., Cini E., Rodriquez M., Carraro F., Taddei M.
Natural Product-Derived Spirooxindole Fragments Serve as Privileged Substructures for Discovery of New Anticancer Agents
Yu B., Zheng Y., Shi X., Qi P., Liu H.
Inhibiting Matrix Metalloproteinases, an Old Story with New Potentials for Cancer Treatment
Stellas D., Patsavoudi E.
New Treatments for Cutaneous Metastatic Melanoma: MAPK Pathway-Targeted and Immune Based Therapies
Ranchon , Boespflug , Rioufol , Schwiertz , Thomas , Dalle
Current and Emerging Strategies in Bladder Cancer
Carradori S., Cristini C., Secci D., Gulia C., Gentile V., Battista Di Pierro G.
Physiological Modulation Approaches to Improve Cancer Chemotherapy : A Review
Kumar R., Kaur M., Silakari O.
Potential New Agents for Chronic Lymphocytic Leukemia Treatment
Rogalinska M., M. Kilianska Z.
Recent Advances in Heterocyclic Tubulin Inhibitors Targeting the Colchicine Binding Site
Wu X., Wang Q., Li W.
Immune Checkpoint Inhibitors for Non-small-cell Lung Cancer: Does that Represent a ‘New Frontier’?
Pilotto S., Kinspergher S., Peretti U., Calio A., Carbognin L., Ferrara R., Brunelli M., Chilosi M., Tortora G., Bria E.
Genetics, Structure, Function, Mode of Actions and Role in Cancer Development of CYP17
Sushko T., Gilep A., Usanov S.
Rational Drug Design for Identifying Novel Multi-target Inhibitors for Hepatocellular Carcinoma
Temirak A., Abdulla M., Elhefnawi M.
Erlotinib in Glioblastoma - Lost in Translation?
Karpel-Massler G., Andrew Westhoff M., E. Kast R., Rainer Wirtz C., Halatsch M.
Mechanisms of Drug Resistance to Vascular Endothelial Growth Factor (VEGF) Inhibitors
Tavakoli J., B. Aragon-Ching J.
Design and Synthesis of 2-substituted [1,2,4]Triazolo[1,5-a]pyrimidines Tethered with Umbelliferone as Selective Carbonic Anhydrase IX and XII Inhibitors
Romagnoli R., Romagnoli E., Brancale A., Supuran C., Nocentini A., Manfreda L., Zanolli A., Bortolozzi R., Viola G.
Nonsteroidal Aromatase Inhibitors for the Treatment of Breast Cancer: An Update
Gobbi S., Rampa A., Belluti F., Bisi A.
Nonsteroidal Aromatase Inhibitors for the Treatment of Breast Cancer: An Update
Gobbi S., Rampa A., Belluti F., Bisi A.
Targeting Tumor Ubiquitin-Proteasome Pathway with Polyphenols for Chemosensitization
Shen M., Hang Chan T., Ping Dou Q.
Clinical Importance and Potential Use of Small Molecule Inhibitors of Focal Adhesion Kinase
Schultze A., Fiedler W.
Overcoming Resistance of Glioblastoma to Conventional Cytotoxic Therapies by the Addition of PARP Inhibitors
J. Chalmers A.
Design, Synthesis, and Molecular Docking Studies of Indolo[3,2-c]Quinolines as Topoisomerase Inhibitors
Badr M., Elmongy E., Sayed I., Moemen Y., Khalil A., Elkhateeb D., Binsuwaidan R., Ali H.
Design and Pharmacophore Study of Triazole Analogues as Aromatase Inhibitors
Banjare L.
Therapeutic Potential of Targeting PAK Signaling
Senapedis W., Crochiere M., Baloglu E., Landesman Y.
New Potent and Selective Inhibitor of Pim-1/3 Protein Kinases Sensitizes Human Colon Carcinoma Cells to Doxorubicin
Moreau P., Dezhenkova L., Anizon F., Nauton L., Thery V., Liang S., Kaluzhny D., Shtil A.
Celecoxib Inhibits Helicobacter pylori-induced Invasion of Gastric Cancer Cells Through an Adenine Nucleotide Translocator-Dependent Mechanism
Lan C., Yang L., Fan L., Zhang Y., Wang J., Guo G., Wan S., Yang S., Wang R., Fang D.
Design of N-substituted Amino Caproic Hydroxamic Acid Histone Deacetylase Inhibitors Reveal an Essential Role for Cap Atomic Composition
M. Brunel J., Salmi-Smail C., Restouin A., Prebet T., Vey N., Collette Y.
Alteration of Ceramide 1-O-Functionalization as a Promising Approach for Cancer Therapy
Ballereau S., Levade T., Genisson Y., Andrieu-Abadie N.
Targeting Receptor Tyrosine Kinase Pathways in Hepatocellular Carcinoma
Wen Chong L., Anh Tuan Luu D., Tzen Jong C., Wei Ling Lam I., Huynh H., Wei Jie Ong R., Yi Qing Li P., Shean Lee S., Yang S.
Exploiting Cyclooxygenase-(in)Dependent Properties of COX-2 Inhibitors for Malignant Glioma Therapy
H. Schonthal A.
Evaluation of Novel Diaza Cage Compounds as MRP Modulators in Cancer Cells
Döring H., Kreutzer D., von Veh J., Ritter C., Hilgeroth A.
Chalcones as Potential Cyclooxygenase-2 Inhibitors: A Review
Mahboubi-Rabbani M., Zarei R., Baradaran M., Bayanati M., Zarghi A.
Recent Advancement in Discovery and Development of Natural Product Combretastatin-inspired Anticancer Agents
O. Patil P., G. Patil A., A. Rane R., C. Patil P., K. Deshmukh P., B. Bari S., A. Patil D., S. Naphade S.
Histone Deacetylase Inhibitors and Colorectal Cancer: what is new?
Tampakis A., Tampaki E., Nebiker C., Kouraklis G.
Differential Expressions of Matrix Metalloproteinases, A Disintegrin and Metalloproteinases, and a Disintegrin and Metalloproteinases with Thrombospondin Motifs and their Endogenous Inhibitors Among Histologic Subtypes of Lung Cancers
Hida Y., Hamada J.
Sphingolipid Modulation: A Strategy for Cancer Therapy
Delgado A., Fabrias G., Bedia C., Casas J., Abad J.L.
Astemizole: an Old Anti-histamine as a New Promising Anti-cancer Drug
Garcia-Quiroz J., Camacho J.
Bioactive Products Targeting C-Met As Potential Antitumour Drugs
Zhao L., Qian C., Ma X., Wang X.
Natural Compounds as Protease Inhibitors in Therapeutic Focus on Cancer Therapy
Kakali B.
Anti-cancer Glycosidase Inhibitors from Natural Products: A Computational and Molecular Modelling Perspective
Singh A., Mhlongo N., Soliman M.
Episensitization: Therapeutic Tumor Resensitization by Epigenetic Agents: A Review and Reassessment
Oronsky B., Oronsky N., Knox S., Fanger G., Scicinski J.
NADPH Oxidases NOXs and DUOXs as Putative Targets for Cancer Therapy
Weyemi U., E. Redon C., R. Parekh P., Dupuy C., M. Bonner W.
Selective Histone Deacetylase Inhibitors
Pan H., Cao J., Xu W.
TEM8 Targeted Cancer Therapy
E. Frankel A., Carter C., Kuo S., Woo J., Mauldin J., Liu J.
Recent Advances and Future Directions in the Management of Metastatic Renal Cell Carcinoma
Ansari J., Glaholm J., McMenemin R., James N., Hussain S.
Advances in VEGFR Inhibitors: A Comprehensive Review of Novel Anticancer Agents
Jha S., Gupta S., Rani S., Arora P., Choudhary N., Kumar S.
The Importance of Structural Water in HDAC8 for Correct Binding Pose Applied for Drug Design of Anticancer Molecules
Morales-Herrejón G., Mendoza-Figueroa H., Martínez-Archundía M., Correa-Basurto J.
Recent Trends of Chalcones Potentialities as Antiproliferative and Antiresistance Agents
Winter E., Locatelli C., Pietro A., Creczynski-Pasa T.
Treatment Directed to Signalling Molecules in Patients with Advanced Differentiated Thyroid Cancer
M.G. Saez J.
Triple-negative Breast Cancer and Poly(ADP-ribose) Polymerase Inhibitors
Park Y., Moriyama A., Kitahara T., Yoshida Y., Urita T., Kato R.
Molecular Probing and Imaging of Histone Deacetylase Inhibitors in Cancer Treatment
Jiaguo H., Zhiguo L., Wenbin Z.
Molecular Field Analysis (MFA) and Other QSAR Techniques in Development of Phosphatase Inhibitors
C. Nair P.
Evolving Therapies and FAK Inhibitors for the Treatment of Cancer
Bullard Dunn K., Heffler M., M. Golubovskaya V.
Development of Novel Indole-3-sulfonamide-heteroaryl Hybrids as Carbonic Anhydrase Inhibitors: Design, Synthesis and in-vitro Screening
Chinchilli K., Singh P., Swain B., Goud N., Sigalapalli D., Choli A., Angeli A., Nanduri S., Yaddanapudi V., Supuran C., Arifuddin M.
Antidepressant Sertraline Hydrochloride Inhibits the Growth of HER2+ AU565 Breast Cancer Cell Line through Induction of Apoptosis and Cell Cycle Arrest
Fayyaz S., Atia-Tul-Wahab , Irshad R., Siddiqui R., Choudhary M.
Mutant B-Raf Kinase Inhibitors as Anticancer Agents
Asati V., Bharti S., Mahapatra D.
Steroidal Cardiac Na+/K+ ATPase Inhibitors Exhibit Strong Anti-Cancer Potential in vitro and in Prostate and Lung Cancer Xenografts in vivo
Dimas K., Papadopoulou N., Baskakis C., Prousis K., Tsakos M., Alkahtani S., Honisch S., Lang F., Calogeropoulou T., Alevizopoulos K., Stournaras C.
Histone Deacetylase Inhibitors as Potential Therapeutic Agents for the Treatment of Malignant Mesothelioma
Katafygiotis P., Giaginis C., Patsouris E., Theocharis S.
New Targeted Therapies for Anaplastic Thyroid Cancer
Antonelli A., Fallahi P., Ulisse S., Martina Ferrari S., Minuto M., Saraceno G., Santini F., Mazzi V., D'Armiento M., Miccoli P.
Dual-Specificity MAP Kinase Phosphatases as Targets of Cancer Treatment
Nunes-Xavier C., Roma-Mateo C., Rios P., Tarrega C., Cejudo-Marin R., Tabernero L., Pulido R.
Emerging AXL Inhibitors in Oncology: Chemical and Biological Advances in Targeted Cancer Therapy
Shah K., Gopal K., Kumar S., Saha S.
Synthesis and Biological Evaluation of Novel Antifolate Analogs as Potential Anticancer Treatment
F. Stoicescu D., Rotaru M.
Docking Studies of Glutamine Valproic Acid Derivative (S)-5- amino-2-(heptan-4-ylamino)-5-oxopentanoic Acid (Gln-VPA) on HDAC8 with Biological Evaluation in HeLa Cells
Martínez-Ramos F., Luna-Palencia G., Vásquez-Moctezuma I., Méndez-Luna D., Fragoso-Vázquez M., Trujillo-Ferrara J., Meraz-Ríos M., Mendieta-Wejebe J., Correa-Basurto J.
Mouse ATP-Binding Cassette (ABC) Transporters Conferring Multi-Drug Resistance
Li S., Zhang W., Yin X., Xing S., Xie H., Cao Z., Zhao B.
Recent Development in Targeting PI3K-Akt-mTOR Signaling for Anticancer Therapeutic Strategies
Qazi A., Hussain A., Hamid A., Qurishi Y., Majeed R., Ahmad M., Najar R., Bhat J., Singh S., Zargar M., Ali S., Saxena A.
Neutrophil Elastase as a Target in Lung Cancer
Moroy G., J.P. Alix A., Sapi J., Hornebeck W., Bourguet E.
Impact of Oncogenic Protein Tyrosine Phosphatases in Cancer
Hardy S., G. Julien S., L. Tremblay M.
Pioneering the Battle Against Breast Cancer: The Promise of New Bcl-2 Family
Boroujeni A., Ates-Alagoz Z.
Genetics, Structure, Function, Mode of Actions and Role in Cancer Development of CYP17
Sushko T., Gilep A., Usanov S.
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