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Therapeutic Exploitation of Apoptosis and Autophagy for Glioblastoma
Kogel D., Fulda S., Mittelbronn M.
Biology and Medicinal Chemistry Approaches Towards Various Apoptosis Inducers
K. Vyas V., Chintha C., R. Pandya M.
Doxycycline in Mitochondrial Mediated Pathway of Apoptosis: A Systematic Review
Sagar J., Sales K., Seifalian A., Winslet M.
Ganglioside GD3 as a Raft Component in Cell Death Regulation
Sorice M., Garofalo T., Misasi R., Manganelli V., Vona R., Malorni W.
Aryl Maleimides as Apoptosis Inducers on L5178-Y Murine Leukemia Cells (in silico, in vitro and ex vivo Study)
Andrade-Jorge E., Godínez-Victoria M., Sánchez-Torres L., Fabila-Castillo L., Trujillo-Ferrara J.
The Alkylating-HDAC Inhibition Fusion Principle: Taking Chemotherapy to the Next Level with the First in Class Molecule EDO-S101
Mehrling T., Chen Y.
Apigenin and Breast Cancers: From Chemistry to Medicine
Nabavi S., Habtemariam S., Daglia M., Nabavi S.
Synthesis and Anticancer Activity Evaluation of Some Benzothiazole-Piperazine Derivatives
Gurdal E., Buclulgan E., Durmaz I., Cetin-Atalay R., Yarim M.
Mitogen-activated Protein Kinase Kinase 6-fusion Protein (MAP2K6-FP) Potentiates the Anti-tumor effects of Paclitaxel in Ovarian Cancer
Yuan J., Kang J., Liao H., Wang X., Nie M., Shuai R., Deng C.
Dinuclear Berenil-Platinum (II) Complexes as Modulators of Apoptosis in Human MCF-7 and MDA-MB231 Breast Cancer Cells
Agnieszka G., Ewa A., Anna B., Krzysztof B., Monika C., Elzbieta S.
The Indolylcoumarin COUFIN Exhibits Potent Activity Against Renal Carcinoma Cells without Affecting Hematopoietic System
Champelovier P., Barbier P., Daras E., Douillard S., Toussaint B., Persoon V., Curri V., Peyrot V., Combes S.
Lipid Rafts, Endoplasmic Reticulum and Mitochondria in the Antitumor Action of the Alkylphospholipid Analog Edelfosine
Gajate C., Mollinedo F.
White Poplar (Populus alba L.) Suspension Cultures as a Model System to Study Apoptosis Induced by Alfalfa Saponins
Balestrazzi A., Carbonera D., Avato P., Tava A.
Suppression of Oncoprotein Her-2 and DNA Damage after Treatment with Flavan-3- ol Vitis labrusca Extract
Scola G., Fernandes Correia Laurino C., Menin E., Salvador M.
Histone Deacetylase Inhibitors as Potential Therapeutic Agents for the Treatment of Malignant Mesothelioma
Katafygiotis P., Giaginis C., Patsouris E., Theocharis S.
Synthesis and Biological Evaluation of Diaryl Ether Linked DC-81 Conjugates as Potential Antitumor Agents
Ramaiah M., Murty J., Sultana F., Bharathi E., Ramakrishna G., Sarma P., Lavanya A., Pushpavalli S., Bhadra M., Kamal A., Viswanath A.
Gambogic Acid is a Novel Anti-cancer Agent that Inhibits Cell Proliferation, Angiogenesis and Metastasis
Wang X., Chen W.
Current and Emerging Strategies in Bladder Cancer
Carradori S., Cristini C., Secci D., Gulia C., Gentile V., Battista Di Pierro G.
Chemotherapeutic Targeting of Cell Death Pathways
Mansilla S., Llovera L., Portugal J.
Inhibition of Hyaluronan Synthase-3 Decreases Subcutaneous Colon Cancer Growth by Increasing Apoptosis
P. Teng B., D. Heffler M., C. Lai E., Zhao Y., M. LeVea C., M. Golubovskaya V., M. BullardDunn K.
FK506 Binding Proteins as Targets in Anticancer Therapy
Romano S., Di Pace A., Sorrentino A., Bisogni R., Sivero L., Fiammetta Romano M.
Discovery of a Novel Co-crystal of Chrysin and Oroxylin A with Anticancer Properties from Leaves of Oroxylum indicum
Singh S., Singh A., Singh A., Devi A., Korimayum M., Singh L.
Cyclic Lipopeptides as Selective Anticancer Agents: In vitro Efficacy on B16F10 Mouse Melanoma Cells
Hmedat A., Morejon M., Rivera D., Pantelic N., Wessjohann L., Kaluderovic G.
Cytotoxic and Apoptotic Impacts of Ceranib-2 on RAW 264.7 Macrophage Cells
Alanyalı f., Algı O.
Shikonin Causes Non-apoptotic Cell Death in B16F10 Melanoma
Ahmad H., Crotts M., Jacobs J., Baer R., Cox J.
Some Wild Mushrooms with High Antioxidant Capacity Exhibit Potent Anticancer Activity on Cancer Cells using the Apoptotic and Antimigration Cell Death Mechanisms
Şebin M., Yılmaz N., Aydın A.
Chloroform Fraction of Drymaria cordata Linn (CFDC) Suppresses Estradiol Benzoate- Induced Endometrial Hyperplasia
Olowofolahan A., Akinjiola O., Olanlokun J., Oyebode O., Aina O., Olorunsogo O.
Cordyceps militaris: A Comprehensive Study on Laboratory Cultivation and Anticancer Potential in Dalton's Ascites Lymphoma Tumor Model
Dutta D., Singh N., Aggarwal R., Verma A.
Bunium persicum Seeds Extract in Combination with Vincristine Mediates Apoptosis in MCF-7 Cells through Regulation of Involved Genes and Proteins Expression
Samandari-Bahraseman M.R., Ismaili A., Esmaeili-Mahani S., Ebrahimie E., Loit E.
A Novel Combinatorial Regimen Using Sorafenib and Uttroside B, A US FDA-designated ‘Orphan Drug’, for the Treatment of Hepatocellular Carcinoma
Keerthana C., Aiswarya S., Rayginia T., Vijayan Y., James S., Shifana S., Sundaram S., Induja D., Lankalapalli R., Harikumar K., Anto R.
A Green Synthesis of Au-Ag Alloy Nanoparticles using Polydopamine Chemistry: Evaluation of their Anticancer Potency Towards Both MCF-7 Cells and their Cancer Stem Cells Subgroup
Zhan H., Ding S., Shen R., Lv Y., Tian X., Liu G., Li C., Wang J.
In Vivo Inhibition of Proteasome Activity and Tumour Growth by Murraya koenigii Leaf Extract in Breast Cancer Xenografts and by Its Active Flavonoids in Breast Cancer Cells
Noolu B., Gogulothu R., Bhat M., Qadri S., Reddy V., Reddy G., Ismail A.
Cytotoxic, Antiproliferative and Apoptotic Effects of New Benzimidazole Derivatives on A549 Lung Carcinoma and C6 Glioma Cell Lines
Yurttas L., Demirayak S., Ciftci G.
A Short Review on the Synthetic Strategies of Duocarmycin Analogs that are Powerful DNA Alkylating Agents
Patil P., Satam V., Lee M.
Dual Induction of Mitochondrial Apoptosis and Senescence in Chronic Myelogenous Leukemia by Myrtucommulone A
Grandjenette C., Schnekenburger M., Morceau F., Mack F., Wiechmann K., Werz O., Dicato M., Diederich M.
A Novel Quinoline Based Second-generation mTOR Inhibitor that Induces Apoptosis and Disrupts PI3K-Akt-mTOR Signaling in Human Leukemia HL-60 Cells
Kumar S., Guru S., Venkateswarlu V., Malik F., Vishwakarma R., Sawant S., Bhushan S.
Differential Role of Apoptosis and Autophagy Associated with Anticancer Effect of Lupulone (Hop β-Acid) Derivatives on Prostate Cancer Cells
Mouratidis P., Colston K., Charolidi N., Pirianov G.
The Effect of Lycopene on the PI3K/Akt Signalling Pathway in Prostate Cancer
Chen J., O'Donoghue A., Deng Y., Zhang B., Kent F., O'Hare T.
Anticancer Agent Ukrain and Bortezomib Combination is Synergistic in 4T1 Breast Cancer Cells
Savran B., Yerlikaya A., Erdoğan E., Genç O.
Differential Effects of Antofine N-Oxide on Solid Tumor and Leukemia Cells
Bour T., Yang X., Li W., Bernardin F., Kaoma T., Muller A., Vallar L., Steinmetz A.
From Na+/K+-ATPase and Cardiac Glycosides to Cytotoxicity and Cancer Treatment
Babula P., Masarik M., Adam V., Provaznik I., Kizek R.
Myricetin Induces Apoptosis in HepG2 Cells Through Akt/p70S6K/Bad Signaling and Mitochondrial Apoptotic Pathway
Zhang X., Chen S., Tang L., Shen Y., Luo L., Xu C., Liu Q., Li D.
Pro-apoptotic Activity of BH3-only Proteins and BH3 Mimetics: from Theory to Potential Cancer Therapy
L. Hartman M., Czyz M.
Genistein Potentiates the Anti-cancer Effects of Gemcitabine in Human Osteosarcoma via the Downregulation of Akt and Nuclear Factor-κB Pathway
Liang C., Li H., Shen C., Lai J., Shi Z., Liu B., Tao H.
Potential Anticancer Properties of Bisphosphonates: Insights From Preclinical Studies
Clezardin P.
Targeting Cell Death and Survival Receptors in Hepatocellular Carcinoma
Muntane J.
Pomegranate Extract, A Prooxidant with Antiproliferative and Proapoptotic Activities Preferentially Towards Carcinoma Cells
H. Weisburg J., G. Schuck A., S. Silverman M., G. Ovits-Levy C., J. Solodokin L., L. Zuckerbraun H., Babich H.
Urea and Thiourea Derivatives of Salinomycin as Agents Targeting Malignant Colon Cancer Cells
Antoszczak M., Mielczarek-Puta M., Struga M., Huczynski A.
Origanum syriacum Induces Apoptosis in Lung Cancer Cells by Altering the Ratio of Bax/Bcl2
Yumrutas O., Yumrutas P., Pehlivan M., Korkmaz M., Kahraman D.
A Combination of EGFR Inhibitors and AE-PDT Could Synergistically Suppress Breast Cancer Progression
Niu Y., Guo X., Han W., Han X., Li K., Tian S., Zhu Y., Bai D., Chen Q.
Synthesis of S-2-phenylchromane Derivatives and Evaluation of the Antiproliferative Properties as Apoptosis Inducers in Cancer Cell Lines
Zhang Y., Ma J., Pei Y., Xie Z., Fu D., Li J.
Germacrone, A Novel and Safe Anticancer Agent from Genus Curcuma: A Review of its Mechanism
Lou G., Huang Y., Wang Y., Chen S., Liu C., Li Y., Feng J.
Erianin as a Promising Novel Agent in the Treatment of Neuroblastoma: The Anticancer Effects and Underlying Molecular Mechanisms
Kocoglu S., Seçme M., Sunay F.
Design and Synthesis of Aspirin-chalcone Mimic Conjugates as Potential Anticancer Agents
Mohamed-Ezzat R., Srour A.
An Active Compound from the Pyrazine Family Induces Apoptosis by Targeting the Bax/Bcl2 and Survivin Expression in Chronic Myeloid Leukemia K562 Cells
Rostampour S., Eslami F., Babaei E., Mostafavi H., Mahdavi M.
Silibinin Induces Both Apoptosis and Necroptosis with Potential Anti-tumor Efficacy in Lung Cancer
Zhang G., Wang L., Zhao L., Yang F., Lu C., Yan J., Zhang S., Wang H., Li Y.
Ginsenoside Rb1 Inhibits the Proliferation of Lung Cancer Cells by Inducing the Mitochondrial-mediated Apoptosis Pathway
Feng L., Liu X., Sun K., Sun Y., Wu W., Chen C., Jin X., Wan X.
Selective Toxicity of Apigenin on Cancerous Hepatocytes by Directly Targeting their Mitochondria
Seydi E., Rasekh H., Salimi A., Mohsenifar Z., Pourahmad J.
Generation of Redox Imbalance Mediates the Cytotoxic Effect of Malabaricone-A in a Multidrug Resistant Cell Line
Manna A., Bauri A., Chattopadhyay S., Chatterjee M.
Recent Trends of Chalcones Potentialities as Antiproliferative and Antiresistance Agents
Winter E., Locatelli C., Pietro A., Creczynski-Pasa T.
Using Cytochalasins to Improve Current Chemotherapeutic Approaches
Trendowski M.
Synthesis and Cytotoxic Properties of Halogen and Aryl-/Heteroarylpiperazinyl Derivatives of Benzofurans
Krawiecka M., Kuran B., Kossakowski J., Cieslak M., Kazmierczak- Baranska J., Krolewska K., Nawrot B.
A Steroidal Na+/K+ ATPase Inhibitor Triggers Pro-apoptotic Signaling and Induces Apoptosis in Prostate and Lung Tumor Cells
Honisch S., Alkahtani S., Kounenidakis M., Liu G., Alarifi S., Al-Yahya H., Dimas K., AlKahtane A., Prousis K., Al-Dahmash B., Calogeropoulou T., Alevizopoulos K., Lang F., Stournaras C.
Garlic-Derived Allyl Sulfides in Cancer Therapy
Cao H., Zhu K., Fan J., Qiao L.
Nature Promises New Anticancer Agents: Interplay with the Apoptosis-related BCL2 Gene Family
Christodoulou M., Kontos C., Halabalaki M., Skaltsounis A., Scorilas A.
Cytotoxicity and Apoptosis Induced by a Plumbagin Derivative in Estrogen Positive MCF-7 Breast Cancer Cells
Sagar S., Esau L., Moosa B., Khashab N., Bajic V., Kaur M.
Cucurmosin Kills Human Pancreatic Cancer SW-1990 Cells in vitro and in vivo
Xie J., Wang C., Yang A., Zhang B., Yin Q., Huang H., Chen M.
Cytotoxicity and Cell Death Mechanisms Induced by a Novel Bisnaphthalimidopropyl Derivative against the NCI-H460 non-small Lung Cancer Cell Line
T. Lima R., A. Barron G., A. Grabowska J., Bermano G., Kaur S., Roy N., Helena Vasconcelos M., K.T. Lin P.
Cinnamaldehyde-Induced Apoptosis in Human Hepatoma PLC/PRF/5 Cells Involves the Mitochondrial Death Pathway and is Sensitive to Inhibition by Cyclosporin A and z-VAD-fmk
Lin L., Tai C., Chang S., Chen J., Wu S., Lin C.
Regulation of Cell Death and Survival by Resveratrol: Implications for Cancer Therapy
Fulda S.
Growth Inhibition of Human Non-Small Lung Cancer Cells H460 By Green Tea and Ginger Polyphenols
Hessien M., El-Gendy S., Donia T., Sikkena M.A.
The Cancer Preventive Effects of Edible Mushrooms
Xu T., B. Beelman R., D. Lambert J.
Resveratrol and Its Analogues: Promising Antitumor Agents
Zhu H.
Doramectin Induces Apoptosis in B16 Melanoma Cells
Crotts M., Jacobs J., Baer R., Cox J.
Targeting RSK2 in Cancer Therapy: A Review of Natural Products
Wu T., Chen Z., Liu X., Wu X., Wang Z., Guo W.
Targeting PPARγ/ NF-κB Signaling Pathway by Britannin, a Sesquiterpene Lactone from Inula aucheriana DC., in Gastric Cancer
Abdolmohammadi M., Roozbehani M., Hamzeloo-Moghadam M., Heidari F., Fallahian F.
Synthesis and in vitro Anti-proliferative Activities on LNCaP, LS180 and MKN45 of Novel 20(R)-Panaxadiol Derivatives
Deng J., Yang X., Luan M., Liu S., Zhang J., Jiang S., Wang W., Hou G., Meng Q., Wang H.
Sinularin Exerts Anti-cancer Effects by Inducing Oxidative Stress-mediated Ferroptosis, Apoptosis, and Autophagy in Prostate Cancer Cells
Wu Z., Su M., Chen H., Chen X., Chen C., An L., Shao Z., Liu X., Lin Y., OuYang A., Liu C.
Newly Synthesized Arylazo Derivatives Induce Apoptosis and G2/M Cell Cycle Arrest With Molecular Docking Validation in Human Cancer Cell Lines
Laboud Y., Hassan N., Hassaneen H., Hassaneen H., Saleh F., Mohamed Teleb M.
Turmeric Extract-loaded Selenium Nanoparticles Counter Doxorubicin-induced Hepatotoxicity in Mice via Repressing Oxidative Stress, Inflammatory Cytokines, and Cell Apoptosis
ALRashdi B., Hussein M., Mohammed R., Abdelhamed N., Asaad M., Alruwaili M., Alrashidi S., Habotta O., Abdel Moneim A., Ramadan S.
Anticancer Potential of a Synthetic Quinoline, 9IV-c, by Inducing Apoptosis in A549 Cell and In vivo BALB/c Mice Models
Mirzaei S., Eisvand F., Nejabat M., Ghodsi R., Hadizadeh F.
Arnicolide D Inhibits Proliferation and Induces Apoptosis of Osteosarcoma Cells through PI3K/Akt/mTOR Pathway
Chen Z., Ni R., Hu Y., Yang Y., Tian Y.
Wortmannin Inhibits Cell Growth and Induces Apoptosis in Colorectal Cancer Cells by Suppressing the PI3K/AKT Pathway
Bani N., Rahmani F., Shakour N., Amerizadeh F., Khalili-Tanha G., Khazaei M., Hassanian S.M., Kerachian M.A., Abbaszadegan M.R., Mojarad M., Hadizadeh F., Ferns G., Avan A.
Biological Potential of Halfsandwich Ruthenium(II) and Iridium (III) Complexes
Ludwig G., Mojić M., Bulatović M., Mijatović S., Maksimović-Ivanić D., Steinborn D., Kaluđerović G.
Neddylation Pathway as a Novel Anti-cancer Target: Mechanistic Investigation and Therapeutic Implication
Jiang Y., Jia L.
Anticancer Activity of Polyether Ionophore-Salinomycin
Antoszczak M., Huczyński A.
Anticancer Activity and Mechanism Investigation of Beauvericin Isolated from Secondary Metabolites of the Mangrove Endophytic Fungi
Tao Y., Lin Y., She Z., Lin M., Chen P., Zhang J.
Bleomycin Induced Sensitivity to TRAIL/Apo-2L-Mediated Apoptosis in Human Seminomatous Testicular Cancer Cells is Correlated with Upregulation of Death Receptors
Timur M., Cort A., Ozdemir E., Sarikcioglu S., Sanlioglu S., Sanlioglu A., Ozben T.
Modulation of Doxorubicin Mediated Growth Inhibition of Hepatocellular Carcinoma Cells by Platelet Lysates
Refolo M., D'Alessandro R., Lippolis C., Messa C., Carella N., Cavallini A., Carr B.
East-West Fusion–Necrosis and Apoptosis Acting in Concert by Demethylcantharidin-Integrated Platinum Complexes
Pang S., So W., Ho Y., Au-Yeung C.
β2-Microglobulin-mediated Signaling as a Target for Cancer Therapy
Nomura T., Huang W., Zhau H., Josson S., Mimata H., Chung L.
Focal Adhesion Kinase Regulates Expression of Thioredoxin-interacting Protein (TXNIP) in Cancer Cells
Ho B., Huang G., Golubovskaya V.
The Role of Autophagic Cell Death and Apoptosis in Irinotecan-treated p53 Null Colon Cancer Cells
John S., Mls J., Cervinka M., Rudolf E.
The Therapeutical Potential of a Novel Pterocarpanquinone LQB-118 to Target Inhibitor of Apoptosis Proteins in Acute Myeloid Leukemia Cells
R. de Souza Reis F., C. Casal de Faria F., P. Castro C., S. de Souza P., da Cunha Vasconcelos F., D. Bello R., J. da Silva A., R.R. Costa P., C. Maia R.
Dendrimer-Curcumin Conjugate: A Water Soluble and Effective Cytotoxic Agent Against Breast Cancer Cell Lines
Debnath S., Saloum D., Dolai S., Sun C., Averick S., Raja K., Fata J.
The Cytotoxic Effect of Emetine and CGP-74514A Studied with the Hollow Fiber Model and ArrayScan Assay in Neuroendocrine Tumors In Vitro
E. Larsson D., B. Hassan S., Oberg K., Granberg D.
Chemoprevention of Breast Cancer by Dietary Compounds
S. Vadodkar A., Suman S., Lakshmanaswamy R., Damodaran C.
Combination Therapy for the Treatment of Pancreatic Cancer
Greenhalf W., Thomas A.
Obesity Modulation - The Role in Carcinogenesis
Legakis I., Syrigos K.
Screening of Bioactive Fractions from Balanites aegyptiaca and Pterocarpus marsupium for Anticancer Effects in HepG2 and U87MG Cells
Vashishth D., Yadav M., Kumar A., Rohilla G., Vashist M., Kataria S.K.
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